法国成监测中心自发报告的性别/性别差异
Héléne Peyriére1,2,3, Ange Dampierre4, Roselyne Vallo5
1Addictovigilance Center, University Hospital, Montpellier, France. h-peyriere@chu-montpellier.fr.
Archives of women's mental health
|July 9, 2024
概括
男性和女性在使用精神活性物质和相关的急性毒性并发症方面表现出不同的模式. 这些性别差异凸显了与物质相关的不良事件的不同风险和结果.
科学领域:
- 药物监督 药物监督 药物监督
- 毒理学 毒理学 毒理学
- 公共卫生 公共卫生
背景情况:
- 了解物质使用和不良事件中的性别和性别差异对于有针对性的公共卫生干预至关重要.
- 以前的研究表明,男性和女性之间物质使用模式和并发症存在差异,但关于急性毒性的具体数据有限.
研究的目的:
- 划分特定的精神活性物质和急性毒性并发症在自发报告 (SRs) 中报告的女性与男性.
- 在法国成警背景下,确定物质使用和相关严重并发症的性别/性别特异性模式.
主要方法:
- 分析了880份与物质相关的急性毒性相关的自发报告 (SRs),这些报告于2021年至2022年期间提交给法国成监测中心.
- 在男性和女性患者组之间对物质类型和并发症概况进行比较的统计分析.
主要成果:
- 严重的并发症在男性 (70.3%) 比女性 (59.5%) 更为普遍.
- 妇女主要报告了精神活性药物 (阿片类药物,二) 与自杀行为作为最常见的并发症 (14.6%).
- 男人主要使用非法物质 (可卡因,安非他命) 或滥用治疗方法,感染率 (12.97%) 和神经问题 (37.6%) 较高.
结论:
- 该研究证实了精神活性物质使用和急性毒性并发症的性别差异显著.
- 调查结果与现有的文献和国家数据一致,强调需要在成警和治疗中采取性别/性别特定的方法.
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