药生物/植物生物配方的方法及其对不同参数的阴道内作用
María Hortencia Miranda1, María Elena Fátima Nader-Macías2
1Centro de Referencia para Lactobacilos, CONICET. Chacabuco 145, San Miguel de Tucumán, CP4000, Tucumán, Argentina.
Veterinary research communications
|July 9, 2024
概括
含有乳酸细菌的益生菌和植物生物配方有效防止牛的产后生殖感染. 这些安全,持久的配方支持有益的细菌,减少有害的细菌,为抗生素提供了替代品.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 微生物学 微生物学
- 动物健康 动物健康
背景情况:
- 产后生殖感染在奶牛中会造成巨大的经济损失.
- 抗生素治疗是一种常见的治疗方法,但引起了人们对耐药性的担忧.
- 乳酸细菌 (LAB) 为预防和治疗这些感染提供了潜在的替代方案.
研究的目的:
- 为牛生殖健康设计和评估益生菌和植物生物配方的长期可行性和安全性.
- 为了评估这些配方对孕母牛的原生阴道微生物群的影响.
- 为了确定基于LAB的治疗方法在预防产后感染方面的有效性.
主要方法:
- 选择的乳酸细菌被纳入益生菌/植物生物配方与植物提取物.
- 配方在产前和产后被静脉注射给孕母牛.
- 评估了微生物群的变化,细菌殖民和安全参数 (营养,临床,血液学,生物化学).
主要成果:
- 在冷藏下,微生物保持了长达9个月的生存能力.
- 肠杆菌菌在分娩后增加,除了用LAB + 蔬菜提取物治疗的奶牛.
- 在所有接受治疗的分娩后组中,LAB数量显著增加,这表明殖民成功.
- 安全参数证实配方无害,没有不良影响.
结论:
- 含有乳酸细菌的益生菌和植物生物配方在预防牛产后生殖感染方面具有活力和安全性.
- 这些配方调节阴道微生物群,促进有益的细菌和抑制病原体.
- 基于LAB的治疗是改善牛的生殖健康的有希望的无抗生素策略.
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