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Updated: Jun 21, 2025

Using Nicotine in a Silica-Exposed Mouse Model to Promote Lung Epithelial-Mesenchymal Transition
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尼克洛萨米德调节人肺动脉光滑肌细胞中的表型切换和炎症反应

Yuwen Lu1, Xiaogan Liang1, Jingwen Song1

  • 1Department of Cardiology, Changhai Hospital, Naval Medical University, 168 Changhai Road, Shanghai, 200433, China.

Molecular and cellular biochemistry
|July 9, 2024
PubMed
概括

尼克洛萨米德 (NCL) 有效地抑制肺动脉光滑肌肉细胞的增殖和迁移,这是肺动脉高血压 (PAH) 的关键因素. 这种重新设计的药物还可以减少炎症,这表明它有可能成为一种新的PAH治疗方法.

关键词:
在NLRP3炎症酶体中,NLRP3炎症尼克洛萨米德 (Niclosamide) 是一种尼克洛萨米德.现象类型的开关肺动脉平滑肌肉细胞肺高血压是一种肺高血压.

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