危地马拉呼吸道共囊病毒流行病的时间变化,2008-2018年
Sarah Hamid1, Laura M Grajeda2,3, Oscar de Leon1,2,4
1Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Influenza and other respiratory viruses
|July 9, 2024
概括
了解危地马拉呼吸道同胞病毒 (RSV) 季节性是免疫接种的关键. RSV流行病显示出显著的时间变化,这表明全年接种疫苗对有风险的婴儿是最优的.
科学领域:
- 流行病学 流行病学
- 病毒学 病毒学
- 公共卫生 公共卫生
背景情况:
- 了解呼吸道同胞病毒 (RSV) 的局部季节性模式对于有效的免疫策略至关重要.
- 危地马拉的RSV发病率模式对于指导及时使用RSV免疫产品至关重要.
研究的目的:
- 为了描述危地马拉RSV的季节性.
- 使用医院监测数据分析与RSV相关的急性呼吸道感染 (ARI).
主要方法:
- 使用移动流行病方法 (MEM) 以RSV相关的ARI的绝对计数.
- 来自危地马拉Santa Rosa和Quetzaltenango部门 (2008-2018) 的医院监测数据.
主要成果:
- 从2008年至2018年间,已发现超过8,487例RSV阳性ARI病例.
- RSV季节的发病时间多达5个月,常见的早期季节 (五月至八月发病) 和观察到的晚期季节 (十月至十一月发病).
- 流行病值准确地捕获了70-99%的年度RSV检测;在监测地点之间,发病和抵消周有显著差异.
结论:
- 危地马拉RSV流行时间的显著变化使得基于过去的季节的准确预测变得复杂.
- 建议全年接种疫苗和免疫预防药物给有风险的婴儿,以最大限度地减少RSV疾病负担.
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