高流量鼻氧疗法用于轻度至中度急性呼吸衰竭的患者,重的胸部创伤:一个探索性描述性研究
Qingcheng Zhu1, Dingyu Tan1, Huihui Wang1
1Department of Emergency Medicine, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou 225001, China.
高流量鼻腔管 (HFNC) 治疗显示,在急性呼吸衰竭的患者中,无创性胸部创伤患者的治疗失败率与非侵入性通风 (NIV) 相似. HFNC提供了更好的患者耐受性,表明其作为呼吸支选择的潜力.
科学领域:
- 紧急医疗 紧急医疗
- 呼吸系统护理 呼吸系统护理
- 创伤外科 手术 创伤外科
背景情况:
- 高流量鼻 (HFNC) 氧气治疗越来越多地用于急性呼吸衰竭 (ARF).
- 对于低血糖ARF中HFNC有效性的证据,特别是在重胸部创伤 (BCT) 患者中,是有限的.
研究的目的:
- 为了比较HFNC与非侵入性通风 (NIV) 的有效性,在患有轻度至中度低血症ARF的BCT患者中.
- 评估HFNC和NIV之间的治疗失败率和患者容忍度.
主要方法:
- 对157名BCT患者的回顾性分析,这些患者患有轻度至中度低血症ARF,接受HFNC或NIV治疗.
- 主要终点:治疗失败 (侵入性通风或切换到其他疗法).
- 二级终点:治疗不耐受.
主要成果:
- 在HFNC (11.1%) 和NIV (16.5%) 组之间,治疗失败率相似 (P=0.366).
- 与NIV (9.4%) (P=0.039) 相比,HFNC表现出明显较低的治疗不耐受性 (1.4%).
- 呼吸困难的恶化是HFNC的主要失败原因,而治疗不耐受是NIV的关键.
结论:
- 在BCT患者中,HFNC是NIV的可行的替代品,用于轻度至中度的低血性ARF,治疗失败率没有增加.
- 与NIV相比,HFNC提供了优越的患者舒适性和耐受性.
- 对于这种患者群体来说,HFNC代表了一种有前途的呼吸支模式.
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