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Updated: Jun 21, 2025

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
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Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

Published on: April 4, 2025

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背后的分子机制 BRACO19 和人类端粒G-四重复相互作用的分子机制

Valeria Libera1, Claudia Fasolato2, Francesca Ripanti1

  • 1Department of Physics and Geology, University of Perugia, via Alessandro Pascoli, 06123, Perugia, Italy.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
|July 9, 2024
PubMed
概括

人类端粒形成G-四重复结构,是药物的关键标. 像K+和Na+这样的酸盐改变了这些结构,影响了像BRACO19这样的药物如何结合,并可能导致病理形式.

关键词:
在BRACO19中,我们使用的是BRACO19圆形二重化谱光学 圆形二重化谱光学光光谱学是一种光谱学.在G-quadruplex中使用.紫外线共振拉曼光谱法紫外线可见吸收光谱学

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