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在海洋无脊椎动物中确定16种吸收紫外线的化合物,使用LC-USI-MS/MS与QuEChERS相结合

Yu-Fang Huang¹, Yan-Jun Liu², Kai-Chien Yang²

¹Institute of Environmental and Occupational Health Sciences, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.

|July 9, 2024

概括

海洋无脊椎动物含有来自个人护理产品的内分泌干扰紫外线吸收化合物 (UVAC). 这项研究检测到16种UVAC,包括二和二-3,引发了环境和健康方面的担忧.

科学领域:

环境化学环境化学
海洋生物学海洋生物学
毒理学毒理学毒理学

背景情况:

紫外线吸收化合物 (UVAC) 在个人护理产品和包装中很常见.
海洋无脊椎动物越来越多地被认为是环境污染物的潜在生物指标.
内分泌干扰化学品 (EDC) 对水生生态系统和人类健康构成风险.

研究的目的:

在海洋无脊椎动物中识别和量化多种UVAC.
评估特定UVAC的流行率和水平,如芬 (BP) 和芬-3 (BP-3).
评估一种敏感的分析方法,用于在海洋生物中检测UVAC.

主要方法:

经过修改的QuEChERS提取技术.
液体染色学UniSpray电离双重质谱法 (LC-USI-MS/MS) 用于UVAC识别.
用矩阵匹配的校准曲线进行准确的量化.

主要成果:

在海洋无脊椎动物中成功识别了16种UVAC,具有高线性 (r ≥ 0.9929).
检测到的UVAC具有较低的检测极限 (0.0061.000 ng/g w.w.) 和定量 (0.0203.000 ng/g w.w.).
发现了BP (100%) 和BP-3 (100%) 的高检测频率,BP和BP-3在显著度下被检测出来,表明了广泛的污染.

结论:

开发的方法有效地检测到海洋无脊椎动物中的UVAC.
在海洋无脊椎动物中,UVACs如BP和BP-3的广泛存在得到证实.
这些发现突出了与海洋生态系统中UVAC污染相关的潜在环境和人类健康风险.

关键词:

索芬是一种基.索芬-3,4-甲基索芬这是EMR-脂质.异构体分离的分离方法

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