身体组成指标与结直肠癌的关联:一项基于医院的病例控制研究
Qiujin Chen1,2, Kai Li3, Yang Liu1
1Department of Clinical Nutrition, The First Hospital of China Medical University, Shenyang, 110001, China.
Journal of cancer research and clinical oncology
|July 9, 2024
概括
低体脂百分比和高内脏脂肪指数会增加结直肠癌的风险. 正常的身体组成与较低的风险有关. 这些体质成分指标与癌症患者的营养状况相关.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 身体组成分析 身体成分分析
背景情况:
- 结肠直肠癌 (CRC) 构成了全球严重的健康负担.
- 关于身体成分 (BC) 与CRC患病率之间的关联存在有限的研究.
研究的目的:
- 研究关键体质成分指标与结直肠癌风险之间的关系.
- 在CRC患者中探索身体组成指标和营养标记之间的相关性.
主要方法:
- 一项涉及303例CRC病例和286例对照者的病例控制研究.
- 使用生物电阻分析,实验室测试,问卷和营养风险评估.
- 在病例组中,在治疗前进行了身体成分分析.
主要成果:
- 低体脂百分比 (BFP) 和高内脏脂肪指数 (VAI) 与CRC风险增加有关.
- 较高的BFP与CRC风险降低相关.
- 正常的BC,以及VAI和BFP,表明CRC风险较低.
- 无脂肪质量指数 (FFMI) 和VAI与前专辑蛋白,血清专辑蛋白和营养风险得分正相关.
结论:
- 低BFP和高VAI是结直肠癌的重要危险因素.
- 在CRC患者中,FFMI和VAI证明了与营养状况标志物的积极关联.
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