加拿大对SARS-CoV-2血清监测的做法:为例行监测和未来的流行病吸取教训
Sheila F O'Brien1,2, Michael Asamoah-Boaheng3,4, Brian Grunau3,4,5
1Epidemiology & Surveillance, Canadian Blood Services, Ottawa, ON, Canada. Sheila.obrien@blood.ca.
概括
加拿大的SARS-CoV-2血清调查面临着由于数据孤岛和各种方法的挑战. 未来的流行病规划需要适应性,可扩展性监测系统,以便及时获得公共卫生数据.
科学领域:
- 公共卫生监督 公共卫生监督
- 流行病学 流行病学
- 传染病控制和控制传染病
背景情况:
- 加拿大的联邦系统需要司法管辖区间协调卫生数据收集.
- 随着COVID-19的流行,人们需要强有力的国家和地区血清监测.
研究的目的:
- 分析加拿大大流行病血清监测倡议 (2020-2023年).
- 确定未来的流行病准备和规划的关键经验.
主要方法:
- 分析了4个国家和7个地区的一般人口SARS-CoV-2血清调查.
- 对13个省和地区管辖区的方法,数据链接和报告结构的评估.
主要成果:
- 测试了超过一百万个样本,但数据被分为11个不同的数据集.
- 方法上的差异 (试验,采样,时间框架) 阻碍了跨区域的比较.
- 调查问卷和健康记录联系的有限使用;干燥的血斑使远程数据收集成为可能.
结论:
- 常规血清监测系统必须具有适应性,灵活性和可扩展性,以适应公共卫生决策.
- 国家规划应优先考虑测试联盟,改进测试能力,数据链接协议和实时通信.
- 这些经验教训将为全面的国家流行病应对计划提供信息,其中包括强有力的血清监测.
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