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Updated: Jun 21, 2025

Studying Cell Cycle-regulated Gene Expression by Two Complementary Cell Synchronization Protocols
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Studying Cell Cycle-regulated Gene Expression by Two Complementary Cell Synchronization Protocols

Published on: June 6, 2017

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FAM122A通过螺旋形动图来抑制B55α/PP2A,确保细胞周期间相进展和检查点控制

Jason S Wasserman1, Bulat Faezov2,3, Kishan R Patel1

  • 1Fels Cancer Institute for Personalized Medicine. Temple University Lewis Katz School of Medicine, Philadelphia, PA, USA.

Nature communications
|July 9, 2024
PubMed
概括

通过阻断基质结合,FAM122A作为蛋白酸酶2A (PP2A) 的竞争性抑制剂. 这种蛋白质调节细胞循环的进展和DNA损伤反应.

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