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Updated: Jun 21, 2025

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ZBP1的凝结物形成协同作用于Z-NAs的识别和信号传导

Feiyan Xie1, Di Wu1, Jing Huang2

  • 1Department of Neurology, Huashan Hospital and School of Life Sciences, State Key Laboratory of Genetic Engineering, Fudan University, 200438, Shanghai, China.

Cell death & disease
|July 9, 2024
PubMed
概括

Z-DNA结合蛋白1 (ZBP1) 形成凝结物以识别Z型核酸并触发抗病毒免疫力. 这个过程涉及ZBP1二分化和RHIM域相互作用,导致对病原体进行编程细胞死亡.

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