患有多发性硬化症的年轻和老年患者的认知和情感思维理论
Maxime Montembeault1, Romane Farley2, Julie Ouellet3
1Douglas Research Center, Department of Psychiatry, McGill University Montréal, Montreal, Quebec, Canada.
Journal of neuropsychology
|July 10, 2024
概括
患有多发性硬化症 (MS) 的老年人经历了认知思维理论 (ToM) 的显著下降,影响了他们理解意图的能力. 这种下降与认知和执行功能有关,而不是核心社会认知缺陷.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 临床神经学 临床神经学
背景情况:
- 心理理论 (ToM) 缺陷在患有多发性硬化症 (pwMS) 的人群中得到了记录.
- 以前的研究往往无法区分认知和情感TOM,并排除了较老的PWMS.
- 没有研究专门研究老年pwMS的ToM.
研究的目的:
- 与健康对照组 (HC) 相比,对患有多发性硬化症 (pwMS) 的年轻人和老年人进行认知和情感TOM的研究.
- 检查pwMS中ToM性能与认知,执行和社会认知措施之间的关系.
- 为了确定年龄是否会加剧 pwMS 中的 ToM 缺陷.
主要方法:
- 招募了四组:年轻的HC,年轻的 pwMS,老年HC和老年 pwMS.
- 利用一个经过调整的基于视频的对话和暗示任务来评估认知和情感ToM.
- 进行了神经心理学电池,包括认知,执行和社会认知评估.
主要成果:
- 观察到TOM条件和组之间存在显著的相互作用.
- 老年pwMS的认知ToM显著低于老年HC和年轻pwMS.
- 认知和情感ToM与全球认知和执行功能相关,但与情感识别或同理心无关.
结论:
- 在pwMS中,认知ToM下降可能会因晚年而加剧.
- 这些障碍很可能与潜在的认知和执行困难有关.
- 核心社会认知障碍似乎并没有成为pwMS中ToM缺陷的基础.
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