在皮肤冠状动脉干预后,HAS-BLED和HEMORR2HAGES出血风险得分的预测值
Ianis Doomun1, Daphné Doomun1, Sara Schukraft1
1Department of Cardiology, University and Hospital Fribourg, Fribourg, Switzerland.
Texas Heart Institute journal
|July 10, 2024
概括
在经皮冠状动脉干预 (PCI) 的患者中,HEMORR2HAGES得分比HAS-BLED或PARIS得分更好地预测出血风险. 高出血风险也与PCI后缺血风险增加和死亡率相关.
科学领域:
- 心脏病学 心脏病学
- 临床风险评估临床风险评估
- 干预心脏病学 干预心脏病学
背景情况:
- 现有的出血风险评分,如HAS-BLED和HEMORR2HAGES被广泛使用,但在接受皮肤冠状动脉干预 (PCI) 的患者中具有有限的验证.
- 准确的出血风险评估对于PCI后的患者管理至关重要,特别是那些接受抗血栓治疗的患者.
研究的目的:
- 在接受PCI的患者中评估和比较HAS-BLED,HEMORR2HAGES和PARIS出血风险得分的预测性表现.
- 评估出血风险得分与重大出血事件或针对患者的综合终点在2年随访期间之间的关联.
主要方法:
- 一项针对2015年至2017年间连续接受PCI的1,080名患者的前性研究.
- 出血风险得分 (HAS-BLED,HEMORR2HAGES,PARIS) 在基线计算.
- 患者被跟踪了2年,以记录主要出血事件 (BARC类型3-5),以及以患者为导向的复合终点.
主要成果:
- 所有评估的出血风险得分都显示出出血事件的统计学显著预测能力.
- 与HAS-BLED (C-统计=0.66) 和PARIS (C-统计=0.66) 相比,HEMORR2HAGES得分在预测严重出血方面表现优越 (C-统计=0.73).
- 被归类为高风险出血的患者经历了以患者为导向的复合终点的更高发病率.
结论:
- 在PCI后预测出血事件时,HEMORR2HAGES,HAS-BLED和PARIS分数是有效的.
- 在PCI患者中,高出血风险与缺血风险增加和2年死亡率增加有关.
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