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在患有炎症性肠病的患者中,眼部肠外表现和治疗方法
Mariana Rodriguez Duran1, Ghazala A Datoo O'Keefe1
1Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, United States.
炎症性肠病 (IBD) 可以导致眼部肠外表现 (O-EIMs),如卵膜炎和表皮炎,可能导致视力丧失. 患有克罗恩病和关节炎的女性患者可能面临这些眼睛疾病的风险更高.
科学领域:
- 眼科医生 眼科 眼科
- 胃肠病学 胃肠病学
- 类风湿病学 类风湿病学
背景情况:
- 肠外表现 (EIM) 影响3-47%的炎症性肠病 (IBD) 患者.
- 眼部EIMs (O-EIMs) 是常见的,影响IBD患者的1.3-86.9%,是受影响的第三个最常见的器官.
- 如果不治疗,O-EIMs可以从轻微的炎症到严重的视力丧失.
研究的目的:
- 在IBD患者中确定常见的O-EIM.
- 评估IBD中开发O-EIM的风险因素.
- 确定O-EIM的患病率是否因人群或IBD亚型而异.
- 探索IBD中常见的O-EIM治疗方法.
主要方法:
- 在IBD患者中对O-EIM进行文献综述.
- 分析与IBD诊断相关的眼部表现.
- 识别常见的O-EIM和相关的风险因素.
主要成果:
- 脑膜炎和脑膜炎是最常见的O-EIM.
- 前性脑膜炎是常见的,但也可能发生后段炎症和视网膜血管炎.
- 视力下降和眼睛疼痛是常见的,通常是不特定的症状.
- O-EIM可能与皮肤和关节EIM同时发生.
- 患有克罗恩病和关节炎的女性患者的风险更高.
结论:
- 在IBD中,O-EIM是一个重要的关注点,需要对视觉投诉进行眼科转诊.
- 早期识别和管理O-EIM对于预防视力损失至关重要.
- 查和意识是很重要的,特别是在风险人群中.
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