更多并不总是更好:在多脉瘤中,手术修饰后的抗生素持续时间
Devon C Freudenberger1, Daniel Scheese1, Luke G Wolfe2
1Division of Cardiothoracic Surgery, Department of Surgery, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
Journal of thoracic disease
|July 10, 2024
概括
传染病 (ID) 专家的参与和手术前的因素显著影响抗生素的持续时间. 然而,无论ID参与或抗生素服用时间长短,患者的结局仍然相似.
科学领域:
- 医学研究 医学研究
- 传染病 传染病 传染病
- 肺部病理学 肺部病理学
背景情况:
- 有限的证据指导了源控制后胸内感染的抗生素持续时间.
- 这项研究调查了手术修饰后的肺部肺部肺脉共症的结果和抗生素持续时间.
- 比较了感染病 (ID) 专家参与和不参与的管理.
研究的目的:
- 为了分析患者的结果后,外科皮手术用于肺部肺部膜.
- 为了比较用和没有ID专家参与管理的病例之间的结果.
- 为了确定预测抗生素持续时间后源控制的因素.
主要方法:
- 对116名患者进行了回顾性图表审查,这些患者因肺部肺部肺部肺部脉凝而接受了外科剪切 (2011年1月至2021年3月).
- 基于ID专家参与的患者特征和结果的比较.
- 线性回归分析以确定抗生素持续时间的预测因素.
主要成果:
- 治疗ID的专家参与 (53.4%) 与更长的抗生素持续时间 (28.7 vs 20.9天) 和更高的IV抗生素使用有关.
- 手术前的因素,如阳性液体培养和呼吸机状态,也预测了更长的抗生素持续时间.
- 术后结果 (复发,再入院,30天死亡率) 在各组之间是相似的.
结论:
- 在皮下除皮术后的肺 empyema 抗生素持续时间取决于 ID 参与,培养结果和呼吸机状态.
- 尽管抗生素持续时间不同,但结果相似,这使得人们质疑最佳治疗时间.
- 需要进一步的随机对照试验来建立基于证据的抗生素指南.
相关概念视频
01:28Pleural Effusion II: Symptoms and Management
162
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
162
01:27Pneumothorax-II
137
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Clinical Manifestations:
137
01:28Pulmonary Tuberculosis V
177
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
177
01:26Tonsillitis II: Management
107
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
107
01:28Pneumonia IV: Management
317
The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
317
01:26Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
71
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
71