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关于中国抗真菌管理的共识 (2024年版)

Feng Ye¹, Shaoxi Cai², Bin Cao³

¹The First Affiliated Hospital of Guangzhou Medical University, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Department of Pulmonary and Critical Care Medicine, Guangzhou Institute of Respiratory Health, Guangzhou National Laboratory, Guangzhou Medical University, Guangzhou, China.

Journal of thoracic disease

|July 10, 2024

概括

这项研究确定了中国22个关键的抗真菌管理 (AFS) 指标,以改善侵入性真菌病 (IFD) 的诊断和治疗,旨在减少药物滥用和改善患者的治疗结果.

科学领域:

医学科学医学科学医学科学
传染性疾病传染性疾病
药理学药理学是指药理学的学科.

背景情况:

侵入性真菌病 (IFD) 构成了严重的全球健康威胁,死亡率和发病率高.
中国面临的挑战包括高误诊率,低于最佳的抗真菌质量和不良事件,导致医疗负担增加.
抗真菌管理 (AFS) 对于改善IFD诊断,优化抗真菌药物使用,提高患者预后和安全至关重要.

研究的目的:

确定和建立一套关键的抗真菌管理 (AFS) 指标,以适应中国的特定环境.
解决迫切需要标准化的AFS实践,以应对该地区入侵性真菌病 (IFD) 带来的挑战.

主要方法:

采用了德尔菲方法,涉及46名来自各个医学领域的权威专家.
衡量标准是根据国际建议选择的,并适应中国的医疗保健环境.
共识被定义为参与专家之间达成80%或更高的共识水平.

主要成果:

在24个初始指标上达成共识,包括正确的患者 (4),正确的时间 (3) 和正确的使用 (17) 类别.
"正确使用"指标进一步详细介绍了药物选择,剂量,降级,持续时间和消费.
最终,经过专家审查和评估,22个指标达到≥80%的协议门.

结论:

这一共识建立了首套专门为中国设计的AFS指标,作为该地区的基本标准.
它代表了亚洲第一个AFS共识,有可能改善IFD诊断和治疗标准.
预计这些指标的实施将指导医院采用AFS,促进合理使用抗真菌药物,并改善患者的治疗结果.

关键词:

抗真菌管理 (AFS) 是一种德尔菲是什么意思德尔菲是什么意思德尔菲是什么意思一致的共识共识.侵袭性真菌病 (IFD) 是一种侵袭性真菌病.这些指标是指标.

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