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风险因素分析和诺莫格拉姆预测模型构建的术后并发症的胸腔镜非小细胞肺癌

Shixin Ma^1,2, Fei Li², Jian Li³

¹Dalian Medical University Graduate School, Dalian, China.

Journal of thoracic disease

|July 10, 2024

概括

这项研究确定了非小细胞肺癌 (NSCLC) 手术后并发症的关键风险因素. 开发了一个名图模型来预测和帮助减少这些胸腔镜肺切除并发症.

科学领域:

胸部外科手术胸部外科手术
在瘤学瘤学.
医疗信息学医疗信息学

背景情况:

在胸腔镜肺切除术后,术后并发症很常见.
减少这些并发症在胸部手术中至关重要.
接受手术的非小细胞肺癌 (NSCLC) 患者面临特定风险.

研究的目的:

分析进行胸腔镜手术的NSCLC患者术后并发症的风险因素.
为这些并发症建立一个名ogram预测模型.
帮助临床决策和改善患者的治疗结果.

主要方法:

872名接受胸腔镜手术的NSCLC患者 (2017-2021) 的回顾性分析.
后勤回归用于识别并发症的独立风险因素.
使用AUC和校准曲线构建和验证名ogram预测模型.

主要成果:

19.6%的患者出现并发症. 确定了独立的危险因素:胸部粘附,呼吸系统疾病史和淋巴细胞-单细胞比率 (LMR).
诺莫格拉姆模型表现出良好的预测性能 (AUC=0.734) 和临床效用.
针对长时间的空气泄漏 (PAL),肺部感染和肺部溢出,确定了特定的风险因素.

结论:

胸部粘附,呼吸道疾病史和LMR是胸腔镜NSCLC手术后术后并发症的重要危险因素.
开发的诺莫格拉姆模型有效预测这些并发症,提供了有价值的临床应用.
该研究提供了一个工具来识别高风险患者,促进有针对性的干预措施.

关键词:

非小细胞肺癌 (NSCLC) 是一种非小细胞肺癌.发生并发症,并发症.命名图形模型命名图形模型胸腔镜 (thoracoscope) 是一个胸腔镜.

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