高蛋白质基配方与异热异基聚合物配方相比,高蛋白质基配方在重症手术患者的效果
Preeda Sumritpradit1, Prapimporn Chattranukulchai Shantavasinkul2,3, Winai Ungpinitpong4
1Division of Trauma Surgery and Surgical Critical Care, Department of Surgery, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand. psumritpradit@gmail.com.
World journal of gastrointestinal surgery
|July 10, 2024
概括
接受高蛋白基配方的重症手术患者保持了体重和肌肉质量,与标准配方患者不同. 这种基于的配方还帮助患者更快地达到热量目标,显示了其在营养支持方面的有效性.
科学领域:
- 关键护理医学 关键护理医学
- 手术营养是指手术营养.
- 胃肠病学 胃肠病学
背景情况:
- 营养不良在重症患者中很普遍,增加了并发症风险.
- 早期的肠道营养非常重要,但要充分实现这一目标是具有挑战性的.
- 基于的配方可能有利于患有食不耐症的患者,但手术ICU的数据有限.
研究的目的:
- 为了比较高蛋白质基配方与手术重症监护室 (SICU) 患者的标准配方.
- 评估对胃肠道耐受性,营养状况和生物化学标记物的影响.
- 为了评估与基配方相关的安全性和不良事件.
主要方法:
- 多中心,双盲,随机对照试验.
- 成年SICU患者 (≥15岁) 接受5-14天的肠道食.
- 高蛋白质基配方与同热/同标准配方14天的比较.
- 评估胃残留体积,营养状况,身体组成和生物化学参数.
主要成果:
- 两组之间胃残留量,体重,身体组成或生物化学参数没有显著差异.
- 标准配方组在体重,BMI和骨肌肉质量方面经历了显著的损失.
- 基于的配方组从基线到第14天保持了体重,BMI和肌肉质量.
- 服用基于的配方的患者比服用标准配方的患者更快地达到热量目标.
结论:
- 高蛋白质基配方是有效和安全的营养支持在SICU患者.
- 这种配方有助于达到热量和蛋白质目标,保持体重和肌肉质量.
- 用专门配方进行早期营养干预对于重症手术患者至关重要.
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