根据三个定义,比较酒精消费和代谢综合征之间的关联:瑞典INTERGENE研究
Alina Skultecka1, Fredrik Nyberg1, Lauren Lissner1
1School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Metabolism open
|July 10, 2024
概括
代谢综合征 (MetS) 与酒精摄入的关联因定义而异. 中等到高的酒精消费可能会降低MetS的几率,特别是在严格的定义下,这需要进一步的研究.
科学领域:
- 心血管健康 心血管健康
- 代谢障碍 代谢障碍 代谢障碍
- 流行病学 流行病学
背景情况:
- 代谢综合征 (MetS) 的患病率根据诊断标准而异.
- 了解酒精消费与MetS之间的关系对于公共健康至关重要.
- 现有的研究还没有完全澄清不同的MetS定义如何影响酒精的关联.
研究的目的:
- 调查不同的代谢综合征 (MetS) 定义如何影响与酒精消费的关联.
- 为了比较各种MetS诊断标准对观察到的酒精-MetS关系的影响.
主要方法:
- 从瑞典INTERGENE队列 (2001-2004) 中对3051名成年人的横截面分析.
- 用于评估乙醇摄入量与根据ATP III,IDF和JIS标准定义的MetS之间的关联的后勤回归.
- 酒精消费被分为禁欲,低,中,高,并根据社会人口统计学,健康和生活方式因素进行调整.
主要成果:
- 梅斯病的患病率在13.9% (ATP III) 到25.3% (JIS) 之间,男性的患病率更高.
- 中高的酒精消费与较低的消费相比,与较低的MetS几率有关,无论MetS的定义如何.
- 只有严格的ATP III定义显示,在完全的共变量调整后,随着乙醇摄入量增加,MetS的几率下降.
结论:
- 酒精消费与MetS的关联是取决于定义的.
- 符合最严格的MetS标准的个人可能会从饮酒中获益.
- 需要进一步的精心控制的研究来证实MetS.中的这些与酒精有关的发现.
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