在治疗性低温症期间的肠道营养策略:谁? 在什么时候? 这是什么?
Simonetta Costa1, Irene Del Rizzo2, Simona Fattore1
1Department of Woman and Child Health and Public Health, Catholic University of Sacred Heart, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy.
Frontiers in pediatrics
|July 10, 2024
概括
在治疗性低温期间,最小的肠道养 (EF) 可以帮助患有缺氧缺血性脑病变 (HIE) 的婴儿更快地达到充分养. 这一策略是有益的,但需要进一步的研究来优化所有HIE婴儿的营养.
科学领域:
- 新生儿科学 新生儿科学
- 儿科胃肠病学 儿科胃肠病学
- 临界护理医学 临界护理医学
背景情况:
- 由于缺乏指导方针,治疗性低温期间和之后的低氧性缺血性脑病变 (HIE) 婴儿的肠道养 (EF) 的临床实践是可变的.
- 目前对治疗性低温症的HIE婴儿进行营养支持的方法缺乏标准化.
研究的目的:
- 评估治疗性低温期间的最小EF策略是否与HIE婴儿完全肠道养的时间缩短有关.
- 确定独立影响HIE婴儿实现完全肠道养的时间的临床变量.
主要方法:
- 从2015年1月到2022年6月在新生儿重症监护病房进行的回顾性研究.
- 在治疗性低温期间获得最小EF的HIE婴儿与没有接受HIE婴儿的比较.
主要成果:
- 接受最小EF的婴儿比没有接受EF的婴儿更快地达到全肠养.
- 最小的EF是快速全肠养的独立有益因素,而机械通风和发作是更长时间完全养的独立因素.
- 最少EF组的婴儿也获得了较短的亲肠道营养和中静脉通道使用时间.
结论:
- 在治疗性低温症期间,最小的肠道养与稳定的HIE婴儿在完全肠道养的时间较短有关.
- 建议进行前性研究,以确定所有HIE婴儿的最佳肠道营养策略,无论临床严重程度如何.
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