在患有初级先天性玻璃眼的儿童手术后的轴长度变化
Hind A Al Dalgan1,2, Ibrahim A Al Obaida1, Adi M Al Owaifeer1,3
1Glaucoma Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Frontiers in ophthalmology
|July 10, 2024
概括
在初级先天性玻璃眼瘤 (PCG) 患者中,眼内压力 (IOP) 变化在手术后显著影响轴长 (AxL). 显著的IOP减少对于PCG儿童的轴长回归至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 儿科手术 儿科手术
- 玻璃眼研究研究 玻璃眼研究
背景情况:
- 初级先天性玻璃眼 (PCG) 提出了诊断和治疗方面的挑战.
- 监测眼内压力 (IOP),光盘,折射和轴长 (AxL) 对于评估手术后的疾病控制至关重要.
- 这项研究的重点是评估儿童PCG患者的玻璃眼外科手术后眼内压力波动的轴长变化.
研究的目的:
- 在患有初级先天性玻璃眼瘤 (PCG) 的儿童中,在玻璃眼瘤手术后,研究眼内压力 (IOP) 和轴长度 (AxL) 变化之间的关系.
- 确定IOP减小对PCG患者轴长回归的影响.
主要方法:
- 在接受眼手术的PCG儿童中,对轴长度 (AxL) 变化的回顾性分析.
- 纳入标准:年龄在4岁以下,未经眼部手术的儿童的眼睛,在2014年6月至2018年7月期间至少接受了一次绿眼瘤手术.
- 使用线性混合效应模型来估计IOP变化对AXL变化的影响.
主要成果:
- 有105只眼睛 (72名儿童) 接受了PCG,并接受了玻璃眼瘤手术.
- 平均基线IOP为26.63 ± 9.57 mmHg,平均基线AxL为21.67 ± 1.82 mm.
- 手术后,平均内血压下降了7.25 ± 12.08 mmHg,平均轴线增加了0.70 ± 1.40 mm.
- 轴长度变化与IOP变化 (p=0.030) 和第一次手术后的时间 (p<0.001) 有显著的关联.
- 在手术后3个月内,需要大幅降低内血压 (≥35 mmHg),以实现轴回归.
结论:
- 眼内压力 (IOP) 的变化对接受手术的初级先天性玻璃眼 (PCG) 儿童的轴长度 (AxL) 变化有显著的影响.
- 在PCG患者的轴长度回归中,需要在手术后大幅减少IOP.
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