脚带炎作为心血管疾病风险升高的潜在早期指标
Kossay Elabd1, Loay Basudan1, Mohammad A Alomari2
1Family Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, SAU.
慢性脚下带炎可能表明系统性炎症,与高C反应蛋白 (CRP) 和糖尿病和高血压等心血管疾病 (CVD) 风险因素的增加有关.
科学领域:
- 整形外科 整形外科 整形外科
- 心脏病学 心脏病学
- 炎症研究 炎症研究
背景情况:
- 脚部带炎会导致部疼痛,通常与生物力学问题和鞋履有关.
- 脚部筋膜炎的系统性影响,特别是与心血管疾病 (CVD) 风险因素的关系,需要更多的研究.
- 这项研究调查了慢性脚下带炎和高C反应蛋白 (CRP) 水平在患有心血管疾病风险因素的个体之间的联系.
研究的目的:
- 探索慢性脚部带炎和CRP水平升高之间的关联.
- 评估脚带炎是否可以作为患有心血管疾病风险因素的患者全身炎症的指标.
- 为了确定脚部筋膜炎与特定心血管疾病风险因素之间的相关性:糖尿病,高血压和脂质失调.
主要方法:
- 一项横截面研究分析了295名患有糖尿病,高血压或脂质失调的患者,不包括具有混CRP因子的患者.
- 临床评估和成像 (超声波或MRI) 用于诊断.
- 研究了脚带炎和CRP升高 (>1 mg/L) 之间的相关性.
主要成果:
- 几乎一半 (47.8%) 的患有脚/脚疼痛的患者被诊断出患有脚下带炎.
- 发现脚带炎和CRP水平升高 (p=0.035) 之间存在显著的关联.
- 升高的CRP水平与糖尿病,高血压和脂质不良症有显著联系;高的BMI也与脚带炎相关.
结论:
- 慢性脚部筋膜炎中CRP水平升高表明与全身炎症有联系,可能增加心血管疾病风险.
- 脚带炎可能作为患有心血管疾病风险因素的患者全身炎症的临床标志物.
- 对于持久部疼痛和已识别的心血管疾病风险因素的人士,建议进行彻底的心血管评估.
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