干白素-1β激活矩阵金属蛋白酶-2以改变眼腺肌皮细胞结构和功能

Junji Morokuma1, Angela Gárriz1, Danny Toribio1

  • 1Department of Comprehensive Care, Tufts University School of Dental Medicine, Boston, MA, United States.

PubMed
概括

干白素-1β (IL-1β) 通过c-Jun N-终端激酶 (JNK) 和矩阵金属蛋白酶-2 (MMP-2) 途径损害眼腺肌皮细胞 (MEC) 功能. 抑制JNK或MMP-2恢复MEC功能,可能改善干眼疾病.

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