根据神经健康人群的体重指数,皮层微观结构的差异,使用结构磁共振成像
Yunseo Park1, Jong Young Namgung1, Chae Yeon Kim1
1Department of Data Science, Inha University, Incheon, Republic of Korea.
Heliyon
|July 10, 2024
概括
体重指数 (BMI) 与大脑皮层微观结构的微妙变化有关,特别是在关联区域. 这些变化可能与负面情绪状态有关,并遵循大脑的结构模式.
科学领域:
- 神经成像是一种神经成像.
- 大脑结构和功能大脑结构和功能
- 人体生理学 人体生理学
背景情况:
- 体重指数 (BMI) 和大脑结构之间的关联正在引起人们的注意.
- 之前的研究主要集中在粗体形态学上,而皮质的微观结构形状未被探索.
- 了解这些微观结构变化对于全面了解BMI的神经影响至关重要.
研究的目的:
- 研究皮质层特定的微结构形状与健康年轻成年人BMI之间的关系.
- 探索BMI如何影响大脑的微观结构组织.
- 识别与BMI相关的微观结构变异相关的特定大脑区域和拓特征.
主要方法:
- 使用微观结构敏感的代理 (T1和T2加权比) 来估计微观结构概况共变率 (MPC).
- 采用了缩小维度的技术,从MPC矩阵中推导出低维梯度.
- 将这些梯度与BMI相关联,并分析与皮质拓学的关联 (表面距离,曲率,状深度).
主要成果:
- 在异模式关联区域中发现了BMI和微观结构梯度之间的显著关联.
- 按BMI梯度的关联遵循皮质拓,涉及到地测距离,曲率和深度.
- BMI梯度关联图与与负面情绪相关的认知状态有关.
结论:
- 体重指数 (BMI) 影响皮质层特定的微观结构形状,特别是在协会皮层.
- 这些微观结构的改变是沿着大脑皮层拓结构组织的.
- 研究结果表明,BMI,皮质微观结构和负面情绪状态之间存在潜在联系,为非典型的大脑组织提供了洞察力.
相关概念视频
Magnetic Resonance Imaging
7.6K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
7.6K
Imaging Studies IV: Magnetic Resonance Imaging
427
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
427


