针在幽灵点的临床效果与化在轻度至中度抑郁症的结合
Yi Wang1, Qun Lu2, Ittipalanukul Penpat3
1Department of Acupuncture and Moxibustion, Shanghai Hospital of Integrated Traditional Chinese and Western Medicine, The Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China.
World journal of psychiatry
|July 10, 2024
概括
针和fluoxetine的联合疗法显著改善了轻度至中度抑郁症患者的抑郁症状和睡眠质量. 这种综合方法显示出较高的疗效和更好的调节神经递质和氧化应激相比,单独使用素.
科学领域:
- 综合医学是一个整体的医学.
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
背景情况:
- 抑郁症是一种普遍,慢性和反复出现的情绪障碍,构成了全球健康挑战.
- 选择性血清素再吸收抑制剂化是一种常见的治疗方法,但单独治疗往往是不够的.
- 幽灵点针对轻度至中度抑郁症有希望,但联合治疗的有效性需要进一步调查.
研究的目的:
- 为了评估在治疗轻度至中度抑郁症时将幽灵点针与fluoxetine化结合在一起的临床有效性.
主要方法:
- 一项对160名轻度至中度抑郁症患者的回顾性研究.
- 患者被分为单独使用fluoxetine (n=80) 的组和联合治疗组 (fluoxetine +针,n=80) 的组.
- 评估了抑郁症的严重程度 (HAMD-24),神经递质水平 (5-HT,NE,DA),氧化应激 (SOD,MDA),睡眠质量 (PSQI) 和副作用 (SERS).
主要成果:
- 组合治疗组的总疗效率 (97.50%) 与仅用素组 (86.25%) 相比显著更高.
- 两组都在抑郁症得分 (HAMD-24),副作用 (SERS) 和睡眠质量 (PSQI) 上有所改善,组合组的改善更大.
- 在8周后,神经递质水平 (5-HT,NE,DA) 和抗氧化剂状态 (SOD) 增加,而氧化应激标志物 (MDA) 在组合组中显著下降.
结论:
- 针在幽灵点与化的结合提供了轻度至中度抑郁症的安全有效治疗方法.
- 这种综合方法改善了抑郁症状,睡眠障碍,神经递质平衡,并减少了氧化应激.
- 结合疗法显示出优越的临床结果,与单独治疗的素相比.
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