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后COVID-19:血液学因素变化患者在三 - 时间间隔
Mohsen Sharifzak1,2,3, Mojtaba Abbasi-Jorjandi2,3, Gholamreza Asadikaram1,2,3
1Applied Cellular and Molecular Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Current medicinal chemistry
|July 10, 2024
概括
血液学参数,如白细胞和红细胞计数,随着COVID-19的严重程度,感染后的时间和性别而发生显著变化. 监测这些血标记物对于管理COVID-19患者至关重要.
科学领域:
- 血液学 血液学 血液学
- 传染性疾病 传染性疾病
- 在COVID-19研究研究中.
背景情况:
- 血液学参数是疾病严重程度和发病性的关键指标.
- COVID-19对各种生理系统产生重大影响,需要进行详细的监测.
研究的目的:
- 为了评估不同COVID-19严重程度阶段的血液学因素.
- 评估这些因素在感染后的不同时间间隔中的变化.
主要方法:
- 分析了470名COVID-19患者 (中度,严重,危急) 的血清样本.
- 在发病后的第一天,1个月和3个月收集样本.
- 测量了全血细胞计 (CBC) 参数,血红蛋白,血红素,hsCRP,G6PD缺乏症和血红蛋白病变.
主要成果:
- 白血球,中性细胞,淋巴细胞,血小板,红血球,Hb,HCT,MCV,MCH和hsCRP水平的显著变化与疾病严重程度相关 (p<0.0001).
- 白血细胞和红血细胞的参数在时间间隔 (p<0.0001) 中显示出显著的变化,不包括单细胞和氨酸.
- 血液和hsCRP水平因性别而异,并且与年龄和BMI相关 (p<0.0001).
结论:
- 血液学和炎症标记因COVID-19的严重程度,时间和性别而有显著差异.
- 这些发现强调了在COVID-19感染期间和之后监测血液学参数对于有效的患者管理的重要性.
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