枣 (Phoenix dactylifera) 对幽默和细胞免疫细胞及其功能的免疫刺激作用
Soukaina Laaraj1, Ibtissam Ouahidi1,2, Nada Al Moudani1
1Laboratory of Microbial Biotechnology and Bioactive Molecules (LM2BM), Faculty of Sciences and Techniques of Fez, Sidi Mohammed Ben Abdellah University, Morocco.
The Egyptian journal of immunology
|July 10, 2024
概括
树果实提取物显著提高免疫细胞活动,增强幽默和细胞免疫力. 这种传统疗法还显示出抗炎和抗氧化特性,这表明它有太阳保护的潜力.
科学领域:
- 免疫学 免疫学 免疫学
- 药理学 药理学是指药理学的学科.
- 自然产品 化学 化学
背景情况:
- 树的果实在摩洛哥传统上用于增强免疫力.
- 需要对其免疫调节作用进行科学验证.
- 了解对免疫细胞和功能的影响至关重要.
研究的目的:
- 为了评估树果树果实提取物的免疫调节作用.
- 评估对免疫细胞功能的影响,如抗体产生,细胞化和T淋巴细胞毒性.
- 探索潜在的化品应用,包括防晒等.
主要方法:
- 制备P. dactylifera水果的水性和乙烯酸提取物.
- 在体内对囊细胞,胸细胞和巨细胞进行测试.
- 测试补充活性,淋巴细胞增殖,T淋巴细胞毒性和细胞.
- 福里埃变换红外光谱仪用于化合物识别.
主要成果:
- 水性提取物通过增加补充活性和囊细胞 (B-淋巴细胞) 增殖 (142.5%) 显著增强了幽默免疫力.
- 观察到细胞免疫的显著刺激与增加的胸细胞增殖 (225%) 和功能 (245.9%).
- 乙酸乙烯提取物通过增强的巨细胞细胞酶表现出抗炎作用,并显示出强大的抗氧化和UV-B吸收特性.
结论:
- 树果实提取物具有显著的免疫刺激,抗炎和抗氧化特性.
- 黄类化合物被确定为主要活性化合物.
- 这些发现支持传统的使用,并表明P. dactylifera提取物在免疫支持和防晒配方中的潜力.
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