营养干预措施减少卡路里的临床影响,一个系统的范围审查
C A J Oudmaijer1, D S J Komninos2, J H J Hoeijmakers3
1Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands; Erasmus MC Transplant Institute, Division of Hepatobiliary and Transplantation Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands; Oncode Institute, Utrecht, The Netherlands.
Clinical nutrition ESPEN
|July 10, 2024
概括
卡路里限制 (CR) 是一种安全且可行的饮食策略. 需要进一步的研究来确认其在不同患者群体中的临床益处.
科学领域:
- 营养科学 营养科学
- 饮食干预 饮食干预
- 卫生研究 卫生研究 卫生研究
背景情况:
- 卡路里限制 (CR) 涉及暂时减少卡路里摄入量.
- 众所周知,CR可诱导弹性和抵抗机制,促进健康.
- 虽然CR的可行性和安全性已在人类身上得到证实,但其益处需要在各种人群中进一步研究.
研究的目的:
- 系统地审查有关类似卡路里限制的干预措施的文献.
- 评估CR在不同人群中的可行性,安全性和潜在益处.
主要方法:
- 系统的范围审查.
- 遵守系统审查和元分析 (PRISMA) 准则的首选报告项目.
- 从3745个初始记录中分析了40项研究.
主要成果:
- 所有包括的研究都证实了CR类干预措施的可行性和安全性.
- 营养先决条件的影响各不相同,突出了需要量身定制的策略.
- 精心设计的策略是必不可少的,考虑到预期的效果,患者群体和后勤限制.
结论:
- 类似于CR的干预措施,包括长期CR和短期禁食,在广泛的患者群体中是可行的.
- 临床上CR的好处,如减少治疗副作用和提高治疗疗效,需要进一步研究.
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