临床和亚临床的动脉样硬化疾病在八年级的人与关节骨折. 一个病例控制研究研究
Aina Capdevila-Reniu1, Margarita Navarro-López1, Cristina Sierra-Benito2
1Orthogeriatric Unit, Department of Internal Medicine, Hospital Clinic de Barcelona, University of Barcelona, Spain.
Medicina clinica
|July 10, 2024
概括
较年长的关节骨折患者比没有骨折的患者表现出更多的亚临床动脉样硬化,如动脉斑块. 然而,临床心血管疾病的发病率在各组之间是相似的,这表明骨折和临床前血管变化之间存在联系.
科学领域:
- 老年学是指老年学的学科.
- 心血管医学 心血管医学
- 整形外科 整形外科 整形外科
背景情况:
- 动脉样硬化和部骨折在老年人中很常见.
- 老年人的动脉样硬化和关节骨折之间的关系尚未完全理解.
研究的目的:
- 为了比较老年患者的临床和亚临床动脉样硬化疾病,有和没有部骨折.
- 在老年人中阐明动脉样硬化和关节骨折之间的联系.
主要方法:
- 一个年龄和性别匹配的病例对照研究,涉及80岁以上的骨折和没有骨折的部骨折.
- 评估血管风险因素,亚临床血管疾病 (状腺斑块,内心介质厚度,动脉硬) 和心血管疾病.
- 使用后勤回归模型来确定动脉样硬化和关节骨折之间的关联的几率比率 (OR).
主要成果:
- 该研究包括每组95名患者,平均年龄为82岁; 77.9%是女性.
- 两组都表现出血管疾病的高发病率 (25%),没有显著差异.
- 与对照组相比,患有关节骨折的患者患有亚临床动脉样变化的患病率更高,特别是心动脉斑块 (OR 3.25 [1.06-9.97]).
结论:
- 患有关节骨折的老年人表现出亚临床动脉样变化的发生率明显较高.
- 与对照组相比,关节骨折患者没有观察到诊断的心血管动脉硬化疾病的增加率.
- 亚临床动脉硬化可能在老年人关节骨折的病理生理学中发挥作用.
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