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Updated: Jun 21, 2025

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困难 Clostridioides 的子是毒素输送载体

Carolina P Cassona1, Sara Ramalhete1, Khira Amara1

  • 1Instituto de Tecnologia Química e Biológica, NOVA University Lisbon, Oeiras, Portugal.

Communications biology
|July 10, 2024
PubMed
概括

艰难杆菌子将毒素TcdA和TcdB输送到肠道,导致肠道疾病. 子表面毒素检测揭示了子作为毒素输送的载体,增强了上皮细胞的结合.

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Fusion of Secretory Vesicles with the Plasma Membrane01:26

Fusion of Secretory Vesicles with the Plasma Membrane

Proteins and neurotransmitters in secretory vesicles can be released from a cell upon vesicle docking, priming, and fusion with the plasma membrane. Vesicles are docked and primed in preparation for the quick exocytosis of their contents in response to a stimulus. The fusion process is mainly carried out by a SNAP Receptor or SNARE complex, consisting of synaptobrevin, syntaxin-1, and SNAP-25.
In 1993, Jim Rothman proposed that the antiparallel pairing of vesicular and transmembrane SNAREs, or...
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