综合饮食抗氧化剂指数与高脂血症之间的关联:NHANES (2005-2020) 的横截面研究
Minli Zhao1, Danwei Zhang1, Qiuping Zhang1
1Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, 350014, China.
Scientific reports
|July 10, 2024
概括
较高的复合食抗氧化剂指数 (CDAI) 水平与降低超脂血症风险有关. 这项研究发现,最佳的CDAI摄入量显著降低了患这种疾病的可能性.
科学领域:
- 营养科学 营养科学
- 心血管健康 心血管健康
- 流行病学 流行病学
背景情况:
- 超脂血是心血管疾病的重要危险因素.
- 饮食中抗氧化剂在预防高脂血症中的作用尚未完全理解.
- 综合饮食抗氧化剂指数 (CDAI) 是衡量整体抗氧化剂摄入量的指标.
研究的目的:
- 调查CDAI与高脂血症之间的关联.
- 为了确定较高的CDAI是否与较低的超脂血症风险有关.
主要方法:
- 利用了2005-2020年国家健康和营养检查调查 (NHANES) 的数据.
- 基于24小时饮食回忆中的六种饮食抗氧化剂计算的CDAI.
- 在30788名美国成年人中使用后勤回归和受限立方线 (RCS) 分析.
主要成果:
- 在CDAI和高脂血症之间发现了显著的负相关性 (OR 0.98;95% CI 0.97-0.99).
- 与最低四分位数 (OR 0.82;95% CI 0.73-0.92) 相比,高CDAI四分位数中的个体患高脂血症的风险降低了1/5.
- RCS分析表明,CDAI和高脂血症风险之间存在线性关系.
结论:
- 保持最佳的CDAI水平与降低超脂血症风险有关.
- 饮食中摄入的抗氧化剂可能对抗高脂血症起着保护作用.
- 在大多数子组中,研究结果一致,突出了饮食抗氧化剂影响的概括性.
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