肺炎或ARDS患者预定的输出管术后的两年存活率:一个前性观察性研究
Xuemin Chai1, Mengyi Ma1, Wenhui Hu1
1Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Chongqing Medical University, Youyi Road 1, Yuzhong District, Chongqing, 400016, P. R. China.
针对肺炎或急性呼吸困扰综合征 (ARDS) 预定抽管后的两年生存率为47.8%. 诸如并发症,疾病严重程度和输出失败等因素显著影响这些危急患者的死亡风险.
科学领域:
- 关键护理医学 关键护理医学
- 肺部病理学 肺部病理学
- 呼吸系统医学 呼吸系统医学
背景情况:
- 患有肺炎或急性呼吸困难综合征 (ARDS) 的患者通常需要机械通风.
- 预定的输出管是这些患者康复过程中的关键步骤.
- 了解脱口术后的长期存活率对于患者管理至关重要.
研究的目的:
- 为了确定肺炎或ARDS患者在成功自发呼吸试验和预定的输出管术后的两年生存率.
- 在这个患者队列中确定两年死亡率的预测因素.
主要方法:
- 在呼吸器重症监护病房进行了前性观察性研究.
- 230名患有肺炎或ARDS的患者通过了自发呼吸试验.
- 数据,包括并发症指数和呼吸功能,在输出前收集,随访两年.
主要成果:
- 两年生存率为47.8%. 这是两年生存率.
- 增加两年死亡率的独立预测因素包括较高的查尔森并发症指数,较高的APACHE II评分,咳峰值流量较弱和输出失败.
- 使用这些因素的预测模型显示出良好的区分能力 (AUC 0.75-0.79).
结论:
- 伴随性疾病,疾病严重程度,咳强度降低和输出失败是预定输出后肺炎或ARDS患者在两年内死亡的重要风险因素.
- 这些发现提供了客观的数据,以帮助在住院和出院后的护理期间的临床决策.
- 识别高风险患者可以促进有针对性的干预措施,以改善长期结果.
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