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在体外抗真菌和物理化学性质的聚合烯酸树脂含有改性酸基玻璃的聚合烯酸树脂
Eun-Jee Jang1, Ye-Ji Hong1, Yoon-Ha Jeong1
1Department of Dental Hygiene, Konyang University, 158 Gwanjeodong-ro, Seo-gu, Daejeon, 35365, Republic of Korea.
BMC oral health
|July 10, 2024
概括
将基基玻璃 (Sr-PBG) 添加到正义牙的烯酸树脂中,可以抑制Candida albicans的生长. 3.75%的Sr-PBG复合物显示出抗真菌特性,具有牙科器械可接受的表面和物理特性.
科学领域:
- 生物材料科学 生物材料科学
- 牙科材料 牙科材料
- 微生物学 微生物学
背景情况:
- 烯酸树脂是可拆卸的正牙器件的标准.
- 设备的卫生状况不佳会促进致病微生物的生长,包括Candida albicans.
- 开发抗微生物正牙材料对于患者健康至关重要.
研究的目的:
- 为了将改性酸基玻璃 (Sr-PBG) 纳入正义牙科的烯酸树脂.
- 评估新型复合物的表面,物理化学性质和体外抗真菌活性,以对抗Candida albicans.
主要方法:
- Sr-PBG被添加到烯酸树脂中,其重量为0% (对照组),3.75%,7.5%和15%.
- 评估了表面的微硬度,接触角度和屈曲强度.
- 在体外对Candida albicans的抗真菌疗效在24小时和48小时后进行了测试.
主要成果:
- 表面微硬度和接触角度在3.75%的Sr-PBG时没有受到影响.
- 实验组的柔性强度下降,但没有显示Sr-PBG度依赖.
- 所有Sr-PBG度在24小时和48小时内都显示出对Candida albicans有显著的抗真菌作用.
结论:
- 3.75%的Sr-PBG在正牙烯酸树脂中提供了有效的抗真菌特性,可以对抗Candida albicans.
- 这种复合材料保持了适合于正应用的物理化学特性.
- Sr-PBG显示了增强可拆卸的正牙器件和降低微生物风险的潜力.
相关概念视频
Carboxylic Acids to Acid Chlorides
Carboxylic acids react with SOCl2 or PCl5 to form acid chlorides. Amongst the carboxylic acid derivatives, acid chlorides are the most reactive and synthetically important derivatives. They are useful reagents for Friedel–Crafts acylation of some aromatic compounds.
Carboxylic Acid Derivatives: Overview
Carboxylic acid derivatives are formed by replacing the hydroxyl group of carboxylic acids with a different functional group. The most common carboxylic acid derivatives are:
Physical Properties of Carboxylic Acid Derivatives
Intermolecular forces dictate several physical properties such as boiling points, melting points, solubilities, and so forth. They are classified into four types: ionic forces, hydrogen bonds, dipole–dipole forces, and dispersion forces. Ionic forces are the strongest, while dispersion forces are the weakest.
Among the carboxylic acid derivatives, the boiling points of acid chlorides and esters are very similar and are the lowest in the series. Acid anhydrides have slightly higher boiling...
Among the carboxylic acid derivatives, the boiling points of acid chlorides and esters are very similar and are the lowest in the series. Acid anhydrides have slightly higher boiling...
Physical Properties of Carboxylic Acids
Carboxylic acids with lower molecular weight exhibit a sharp and unpleasant odor. They also have higher boiling and melting points than analogous compounds, such as aldehydes, ketones, and alcohols.
Substituent Effects on Acidity of Carboxylic Acids
The acidity of carboxylic acids is influenced by the nature of the substituents bounded to the functional group. The acid strength is determined by the stability of the carboxylate anion—the conjugate base formed by dissociating the corresponding carboxylic acid.
Bioplastics
Bioplastics derived from microbial processes present a sustainable alternative to conventional petroleum-based plastics. Among these, polyhydroxyalkanoates (PHAs), particularly polyhydroxybutyrates (PHBs), have emerged as prominent candidates due to their biodegradability and biocompatibility. These polymers are synthesized by a variety of bacteria, such as Cupriavidus necator and Pseudomonas putida, which naturally accumulate PHAs as intracellular carbon and energy reserves, especially under...

