对恶性贫血症状的系统审查
Catherine Heidi Seage1, Alexis Bennett2, Nicola Ward3
1Cardiff School of Sport & Health Sciences, Cardiff Metropolitan University, Cardiff, Wales, United Kingdom.
Food and nutrition bulletin
|July 10, 2024
概括
恶性贫血 (PA) 在成年人中表现出各种症状,如疲劳和肢体感觉丧失. 了解这些症状对于及时诊断和治疗这种自身免疫性疾病至关重要.
科学领域:
- 血液学 血液学 血液学
- 免疫学 免疫学 免疫学
- 胃肠病学 胃肠病学
背景情况:
- 恶性贫血 (PA) 是一种与自身免疫性胃炎相关的宏细胞贫血.
- 医疗保健提供者对PA症状和诊断标准的认识需要改进,以便及时诊断和治疗.
研究的目的:
- 系统地审查和记录成人PA病例研究中的症状和临床并发症.
- 为了增强目前对PA呈现的临床理解.
主要方法:
- 对 PsycINFO,Embase 和 MEDLINE 数据库进行系统的文献搜索.
- 根据"国际疾病分类"对症状进行分类.
- 根据成年AP病例记录的频率对症状进行分组.
主要成果:
- 在103名被诊断患有PA的成年人中记录了症状.
- 最常见的症状包括疲劳 (55%),肢体感觉丧失 (32%),体重减轻 (27%) 和舌头疼痛 (23%).
- 有记录的症状与维生素B12和叶酸缺乏一致.
结论:
- 成年人PA表现出各种症状,基本上与B12和叶酸缺乏一致.
- 需要进一步的研究来确定症状集群,这些症状可以促使怀疑B12缺乏症的诊断测试.
- 更好地了解PA症状可以帮助早期检测和管理.
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