定义新生儿和婴儿的最佳可巴拉明状态
1Laboratory of Medical Biochemistry, Innlandet Hospital Trust, Lillehammer, Norway.
Food and nutrition bulletin
|July 10, 2024
概括
婴儿中可巴胺 (维生素B12) 缺乏会导致发育迟缓. 早期诊断和用基巴胺治疗对于预防永久性神经损伤至关重要.
科学领域:
- 儿科 儿科 儿科
- 营养科学 营养科学
- 神经学 神经学
背景情况:
- 最佳的可巴胺 (维生素B12) 状态对于健康的婴儿神经发育至关重要.
- 科巴胺缺乏症是新生儿和幼儿的一个重大问题.
研究的目的:
- 描述婴儿科巴拉明缺乏症的流行病学,病理生理学和诊断挑战.
- 为预防这一年龄段人群中可巴拉明缺乏症提供指导.
主要方法:
- 对婴儿科巴拉明缺乏症现有文献的综述.
- 临床表现和诊断标记的分析.
主要成果:
- 由于母亲的缺乏,长时间的母乳养和推迟引入动物性食品,婴儿中常见的是巴胺缺乏症.
- 症状包括食困难,吐和便秘,以及神经发育延迟.
- 早期检测和干预对于预防不可逆转的神经损伤至关重要.
结论:
- 临床怀疑可巴拉明缺乏症需要立即进行生物化学测试.
- 血总同类半氨酸水平升高 (>5.0μmol/L) 证实了可巴拉明缺乏症.
- 治疗包括肌肉内注射基巴胺,然后进行饮食调整.
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