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Updated: Jun 21, 2025

Pooled shRNA Library Screening to Identify Factors that Modulate a Drug Resistance Phenotype
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针对NEAT1和AURKA作为多发性骨髓瘤新潜在治疗选择的组合策略

Noemi Puccio1, Gloria Manzotti2, Elisabetta Mereu3

  • 1Laboratory of Translational Research, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia; Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena.

Haematologica
|July 11, 2024
PubMed
概括

抑制NEAT1和AURKA一起通过破坏细胞分裂来阻止多发性骨髓瘤 (MM) 细胞生长. 这种针对NEAT1和Aurora Kinase A (AURKA) 的组合疗法对治疗预后不佳的MM患者有很大的前景.

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