CircGNAO1加强其宿主基因GNAO1的表达,以抑制肝癌发生

Hongwei He1, Qing Zhang2, Qiyun Gu1

  • 1Department of Hepatobiliary Surgery, Jinshan Branch of Shanghai Sixth People's Hospital, Shanghai Jiaotong University, Shanghai, 201599, China.

Heliyon
|July 11, 2024
PubMed
概括

循环RNA GNAO1 (circGNAO1) 在肝细胞癌 (HCC) 中是下调的. 过度表达circGNAO1通过上调其宿主基因,瓜核酸结合蛋白,α激活活性聚O (GNAO1),抑制癌症发展来抑制HCC的进展.

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