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骨矿物质密度与发生的高强度背痛无关:10年男性队列研究
Mahnuma M Estee1, YuanYuan Wang1, Stephane Heritier1
1School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria 3004, Australia.
JBMR plus
|July 11, 2024
概括
低骨密度 (BMD) 与男性随着时间的推移发展严重的背痛或残疾无关. 这项研究没有发现BMD和事件疼痛之间的联系,挑战了常见的信念.
科学领域:
- 老年学和老年医学是老年学和老年医学.
- 风湿病学和肌肉骨疾病
- 公共卫生和流行病学
背景情况:
- 患者的感知将骨质疏松症与疼痛联系在一起,与医疗保健提供者的观点相反,疼痛主要发生在骨折时.
- 缺乏使用公正的黄金标准措施的社区人口骨矿物质密度 (BMD) 和背痛的纵向数据.
研究的目的:
- 为了研究骨矿物质密度 (BMD) 与高强度背痛和/或高残疾发生率之间的纵向关联,超过10年.
- 为了检查澳大利亚男性在基线没有高强度症状的这种关系,使用公正的黄金标准措施.
主要方法:
- 一组441名澳大利亚男性,最初没有高强度背部疼痛/残疾,被跟踪了10年.
- 用DXA (双能X射线吸收计) 测量骨矿物质密度 (BMD) 在腰椎和全部.
- 背部疼痛和残疾被评估使用等级慢性疼痛量表;用于调整混因子的逻辑回归.
主要成果:
- 在任何部位 (腰椎或全部) 的基线BMD与高强度背痛或高残疾的发展之间没有发现显著的关联.
- 在441名参与者中,37名男性在10年的随访期间出现了高强度疼痛和/或高残疾.
- 经过调整后的分析证实,骨髓硬化不是发生高强度疼痛或残疾的预测因素.
结论:
- 骨矿物质密度 (BMD) 与社区男性发生的高强度背痛或残疾无关.
- 这些发现挑战了人们普遍认为低骨密度是导致背痛和残疾的直接原因的观点.
- 进一步的研究可能会探索其他因素,导致老年人群的背痛.
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