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Updated: Jun 21, 2025

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在异常性肺动脉高血压中识别STIM1基因的非编码功能调节变异

Bingxun Liu1,2, Cen-Jin Wen3,4, Guangyuan Zhou1,2

  • 1Department of Pathophysiology, School of Basic Medicine (B.L., G.Z., Z.W., T.Z., Y.Z., S.Q., L.Z., Q.H.), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Hypertension (Dallas, Tex. : 1979)
|July 11, 2024
PubMed
概括

在STIM1中,有三种非编码变异与异常性肺动脉高血压 (PAH) 相关. 一种变体rs1561876-G增强了STIM1的转录活性,促进了细胞增殖和信号传递,这表明它在PAH发展中发挥了作用.

关键词:
斑点,西部风格,西方风格微RNAs 是一个微型RNA.肌肉,光滑的 肌肉,光滑的肺动脉高血压 肺动脉高血压肺动脉中的肺动脉.

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