尿液分析可以预测有或没有导管的男性是否缺少尿路感染
Paul Oh1, Kevin C Lewis1, Daniel A Shoskes1
1Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Neurourology and urodynamics
|July 11, 2024
概括
阴性尿液分析 (UA) 准确预测男性无尿路感染 (UTI). 这表明尿液培养只需要异常的UA结果,因为常见的切断错过了一些尿路感染.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
- 临床诊断 临床诊断 临床诊断
背景情况:
- 尿路感染 (UTI) 在男性中很常见.
- 准确的诊断方法对于及时治疗至关重要.
- 尿液分析 (UA) 和尿培养值在男性尿路感染诊断中的作用需要澄清.
研究的目的:
- 评估阴性尿液分析 (UA) 在预测阴性尿液培养和男性无尿道感染的准确性.
- 确定最佳的尿培养生长切断点,以诊断男性的尿路感染,有和没有尿导管.
主要方法:
- 在一周内对22883个UA和成年男性的尿液培养进行了回顾性评估.
- 计算尿路感染不存在的预测值,定义为缺乏记录的尿路感染诊断,抗生素处方或尿路病原体在培养物中的存在.
主要成果:
- 阴性UA在整体队列中显示了阴性尿液培养 (0.95) 和无尿路感染 (0.99) 的高预测值.
- 在持久性尿导管的男性中,阴性UA还显示了阴性尿培养 (0.93) 和无尿路感染 (0.99) 的高预测值.
- 对于尿液培养生长的10万个殖民地形成单位 (CFU) /毫升的常规切断值未能确定22%的尿路感染.
结论:
- 阴性UA是排除男性尿路感染的可靠指标,支持其用于指导尿液培养订单.
- 传统的100,000 CFU/mL尿液培养切断值可能会错过男性人口中大量的尿路感染子集,这需要进一步调查.
相关概念视频
Disorders of the Urinary System
278
The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
278
Factors Affecting Renal Clearance: Renal Impairment
74
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
74
Physiology of Urine Formation
3.6K
Urine formation is an essential function of the human body. It plays a critical role in maintaining homeostasis by regulating the volume and composition of body fluids. The kidneys, the primary organs involved in this process, filter blood to remove waste products and excess substances, ultimately producing urine.
Glomerular Filtration
The first stage in urine formation is glomerular filtration. Each kidney contains approximately 1 million nephrons, the functional units of filtration, with a...
Glomerular Filtration
The first stage in urine formation is glomerular filtration. Each kidney contains approximately 1 million nephrons, the functional units of filtration, with a...
3.6K


