长期的自然历史的假设的突出血流
Peerapol Wangrattanapranee1,2, Usah Khrucharoen1,3,4,5, Dennis M Jensen1,3,4,5
1VA GI Hemostasis Research Unit, Los Angeles, California, USA.
大多数患有假定分分管出血 (TICH) 的患者不会再次出血. 然而,再出血与高血压和心血管疾病的新诊断有关,影响长期结果.
科学领域:
- 胃肠病学 胃肠病学
- 临床医学 临床医学
- 血液研究研究出血.
背景情况:
- 被诊断为推定TICH的患者的自然病史没有得到充分的记录.
- 了解再出血率和结果对于患者管理至关重要.
研究的目的:
- 为了确定假定TICH患者的再出血率和临床结果.
- 为了调查转换率到最终的TICH.
- 为了确定与TIC再出血相关的风险因素.
主要方法:
- 对从1994年到2023年前性收集的数据进行了回顾性队列研究.
- 纳入标准:假定没有其他出血原因的TICH,至少6个月的随访.
- 诊断方法包括内镜,成像和扫描.
主要成果:
- 在139名假定TICH患者中,24.5%的患者在中位数73个月的随访期间经历了再出血.
- 56%的复出血患者被诊断出确定的TICH,显示出更高的再入院,再干预和手术率.
- 新诊断的高血压和动脉样性心血管疾病是再次出血的重要危险因素.
结论:
- 在假定TICH患者中,75.5%的患者长期没有再出血.
- 显著比例的重出血者被证实是最终的TICH.
- 高血压和心血管疾病被确定为分流动脉出血再出血的关键风险因素.
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