相关实验视频

Updated: Jun 21, 2025

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
05:33

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines

Published on: November 9, 2020

9.6K

针对免疫治疗的向蛋白质降解 (TPD):了解向基米拉驱动的乌比奎丁-蛋白质酶相互作用的蛋白质分解

Rajamanikkam Kamaraj1, Subhrojyoti Ghosh2, Souvadra Das3

  • 1Department of Pharmacology and Toxicology, Faculty of Pharmacy, Charles University in Prague, Heyrovskeho 1203, 50005 Hradec Kralove, Czech Republic.

Bioconjugate chemistry
|July 11, 2024
PubMed
概括

向蛋白质降解 (TPD) 使用小分子来消除引起疾病的蛋白质. 本次审查强调了TPD,特别是PROTACs在治疗疾病方面的进展以及免疫治疗的潜力.

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A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes07:59

A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes

Published on: March 25, 2014

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Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs10:44

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs

Published on: May 15, 2019

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Targeted Cancer Therapies

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The Proteasome01:13

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