新生儿重症监护病房新生儿药物管理错误的临床和经济影响
Josephine Henry Basil1, Nurul Ain Mohd Tahir1, Chandini Menon Premakumar1
1Centre for Quality Management of Medicines, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
PloS one
|July 11, 2024
概括
新生儿重症监护室的药物管理错误往往是中度的,每次错误平均花费14.04美元. 关键因素包括静脉注射和高警报药物,需要改善新生儿安全策略.
科学领域:
- 新生儿重症监护室新生儿重症监护室
- 患者的安全性 患者安全性
- 卫生经济学 卫生经济学
背景情况:
- 尽管采取了安全措施,但药物管理错误 (MAE) 仍然很普遍,影响了临床结果和医疗保健成本.
- 关于临床影响评估工具和MAE的经济负担,特别是新生儿群体的研究有限.
- 这项研究通过评估新生儿重症监护室 (NICU) 中 MAE 的临床和经济后果来弥补这一差距.
研究的目的:
- 确定NICU中药物管理错误的潜在临床和经济影响.
- 确定与这些错误的发生和严重程度相关的因素.
- 为在新生儿护理中实施有针对性的错误减少策略提供证据.
主要方法:
- 在马来西亚五家公立医院的NICU进行了前性,直接观察性研究.
- 临床药剂师独立评估药物错误,专家小组使用视觉模拟尺度评估临床和经济结果.
- 多项和多重线性回归分析确定了与错误严重程度和成本相关的因素.
主要成果:
- 在1288次观察到的药物管理中,1018次 (79.0%) 的错误可能是中度严重的,30次 (2.3%) 可能是严重的.
- 估计的总潜在经济影响为27,452.10美元,平均成本为每次错误14.04美元.
- 与严重错误相关的因素包括静脉注射,高警报药物,缺乏协议和较年轻的新生儿;成本与静脉注射路线和高警报药物有关.
结论:
- 在NICU中药物管理错误主要是中度严重的,造成了重大经济成本.
- 静脉注射和使用高警报药物是错误严重程度和成本的关键驱动因素.
- 实施有效的减少错误策略对于提高重症监护机构新生儿患者安全至关重要.
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