从2007年到2020年,韩国对青光眼药物的处方趋势:一项全国性基于人口的研究
Kyeong Ik Na1, Won June Lee2, Youn Joo Choi1
1Department of Ophthalmology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
PloS one
|July 11, 2024
概括
青光眼的药物治疗趋势显示,每位患者处方眼滴的数量没有变化. 然而,固定组合眼液的使用量增加,导致在14年内每处方使用的活性成分增加.
科学领域:
- 眼科医生 眼科 眼科
- 药理学 药理学是指药理学的学科.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 玻璃眼是全球不可逆转的失明的主要原因.
- 有效的药物管理对于预防青光眼患者的视力丧失至关重要.
- 了解长期处方趋势可以为临床实践和公共卫生策略提供信息.
研究的目的:
- 为了研究长期趋势在韩国青光眼药物处方模式.
- 分析2007年至2020年间使用的青光眼药类型和组合的变化.
主要方法:
- 韩国医疗保险审查和评估服务数据库的回顾性分析.
- 包括所有从2007年到2020年处方眼药的青光眼患者.
- 权衡的处方分析,以考虑个体患者处方频率.
主要成果:
- 前列腺素模拟单一治疗是最常见的处方类型.
- 观察到从β阻塞单一治疗到固定组合眼滴的转变是第二个最常见的情况.
- 固定组合眼滴处方显著增加 (1.291%/年),单成分处方减少 (-1.290%/年).
- 每名患者的青光眼眼滴数量没有显著变化 (平均1.302).
- 每名患者的活性成分数量显著增加 (0.01737/年),从1.659增加到1.896.
结论:
- 虽然每名患者的青光眼滴量保持稳定,但治疗的复杂性增加.
- 固定组合眼滴的增加有助于增加每处方活性成分的数量.
- 这些发现为优化未来的玻璃眼治疗策略和药物管理提供了洞察力.
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