源不明的发烧:哥伦比亚12年的病例系列
Juan Manuel Vásquez-Jiménez1, Sebastián Mackenzie1, Jorge Pulido-Arenas1
1Department of Internal Medicine, Hospital Universitario San Ignacio, Pontificia Universidad Javeriana. Bogotá D.C., Colombia.
Journal of infection in developing countries
|July 11, 2024
概括
哥伦比亚的未知起源发烧 (FUO) 的原因与发达国家相似,结核病是最常见的诊断. 断层扫描引导的活检是诊断的关键.
科学领域:
- 传染性疾病 传染性疾病
- 内部医学 内部医学
- 临床诊断 临床诊断 临床诊断
背景情况:
- 源不明发烧 (FUO) 是一个具有多种原因的诊断挑战.
- 病因学因地区和资源的可用性而异.
- 这项研究研究了哥伦比亚参考中心12年来FUO病例.
研究的目的:
- 描述FUO的临床特征和病因.
- 评估FUO管理中的诊断辅助工具的实用性.
- 在拉丁美洲背景下分析FUO案例.
主要方法:
- 成年FUO患者 (2006-2017年) 的回顾性病例系列.
- 纳入标准:发烧>3周,在住院3天后未被诊断出来.
- 电子医疗记录被用于病例识别.
主要成果:
- 有112例符合标准 (平均年龄为43岁,66%为男性).
- 确定的病因:感染性 (31.2%),炎症性 (20.5%),瘤性 (14.3%).
- 结核病 (17%),霍奇金淋巴瘤 (7.1%),SLE (6.3%) 是最常见的;31.2%的人仍未被诊断出来.
- 对比断层扫描和活检对于诊断至关重要.
结论:
- 拉丁美洲的病因与发达国家的病因相似.
- 在这个哥伦比亚队列中,结核病是FUO的主要原因.
- 以断层扫描为指导的侵入性研究对于诊断FUO至关重要.
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