预测癌症患者在治疗前的心率变化使用失眠认知行为疗法逐步治疗的反应
James Garneau1, Josée Savard2, Thien Thanh Dang-Vu3
1Department of Psychology, Concordia University, 7141 Sherbrooke St. W, Montréal, H4B 1R6, Canada; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal (CRIUGM), CIUSSS Centre-Sud-de-l'île-de-Montréal, 4565 Queen Mary Rd, Montréal, H3W 1W5, Canada.
Sleep medicine
|July 11, 2024
概括
高频率心率变化 (HF-HRV) 没有预测癌症患者对失眠认知行为疗法 (CBT-I) 的治疗反应. 这些发现表明HF-HRV不是定制CBT-I强度的可靠生物标志物.
科学领域:
- 心理学 心理学 心理学
- 心脏病学 心脏病学
- 在瘤学瘤学.
背景情况:
- 失眠在癌症患者中很常见.
- 失眠的认知行为疗法 (CBT-I) 是有效的.
- 需要CBT-I反应的预测器来个性化治疗.
研究的目的:
- 调查高频心率变化 (HF-HRV) 和其反应性是否预测对CBT-I的反应.
- 为了在标准和阶段性护理模型中对患有失眠的癌症患者进行检查.
主要方法:
- 177名患有失眠的癌症患者被随机分配到逐步护理或标准CBT-I.
- 心率变化 (HRV) 在休息和焦虑期间被测量.
- 使用失眠严重程度指数 (ISI) 和睡眠日记来评估失眠症状.
主要成果:
- 休息的HF-HRV与初始睡眠效率和延迟相关,但不是ISI.
- 休息HF-HRV没有预测整体失眠变化或对治疗强度的差异性反应.
- HRV反应性与任何结果措施都没有关联.
结论:
- 高频率-高频率测量不能预测癌症患者对CBT-I的纵向治疗反应.
- 对于这一群体来说,高频率-高频率-高频率并不是指导治疗强度的合适生物标志物.
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