磁共振温度计用于口腔喉区域的高温症
Theresa V Feddersen1,2, Juan A Hernandez-Tamames2,3, Margarethus M Paulides1,4
1Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, the Netherlands.
概括
磁共振温度计 (MRT) 是可行的头高温治疗,显示呼吸或吞的最小影响. 性能因解剖区域而异,部肌肉产生最好的结果.
科学领域:
- 医疗成像医学成像
- 生物物理学的生物物理.
- 在瘤学瘤学.
背景情况:
- 磁共振温度计 (MRT) 提供非侵入性,实时的3D温度监测,对于高温症治疗至关重要.
- 呼吸和吞等生理过程中的运动器件对头部和部区域的MRT构成挑战.
- 长时间的治疗时间 (60-90分钟) 需要强大而可靠的温度监测.
研究的目的:
- 评估口腔喉MRT在高温症治疗中的临床可行性.
- 量化呼吸和吞对头部和部MRT性能的影响.
- 为了评估MRT在头部和部的不同解剖区域的准确性.
主要方法:
- 使用3D-ME-FGRE序列进行MRT采集.
- 在大约75分钟内对5名志愿者进行了幻影研究和体内扫描.
- 研究了加速 (ARC=2) 和不同图像平均值 (NEX=1,2,3) 对MRT性能的影响.
- 在志愿者中获得的呼吸屏蔽扫描和有故意吞的扫描.
- 在部肌肉,脊髓和肌肉中使用平均平均误差 (MAE),平均误差 (ME) 和空间标准偏差 (SD) 量化MRT性能.
主要成果:
- 幻影研究显示NEX增加显著减少SD,但没有影响MAE或ME.
- 志愿者扫描显示,屏息和吞扫描之间没有显著的性能差异.
- 在各种解剖学区域观察到MRT性能的显著变化:部肌肉 (MAE=1.96°C,SD=0.82°C),脊髓 (MAE=3.17°C,SD=0.92°C) 和按摩器肌肉 (MAE=4.53°C,SD=1.16°C).
- 脊髓表现出最好的ME (-0.64°C),其次是部肌肉 (1.15°C) 和按摩器肌肉 (-3.05°C).
结论:
- 在高温治疗期间,MRT在临床上可用于监测口腔喉温度.
- 呼吸和吞等生理运动,以及成像参数 (ARC,NEX) 在该区域没有显著降低MRT性能.
- 感兴趣区域 (ROI) 的选择显著影响MRT的准确性和可靠性,强调需要根据临床目标进行仔细选择.
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