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以波罗的海水域为例的制药排放:用多层预测模型比较测量结果

Vaidotas Kisielius¹, Lauri Äystö², Terhi Lehtinen³

¹Department of Environmental Science, Aarhus University, Frederiksborgvej 399, Roskilde 4000, Denmark.

Journal of hazardous materials

|July 11, 2024

概括

废水中的药品对波罗的海等水生生态系统构成风险. 精制预测模型以排泄和清除率显著提高预测环境水平的准确性.

科学领域:

环境化学环境化学
生态毒理学生态毒理学
水质管理水质管理

背景情况:

在水生环境中越来越多地检测到药物和有的X射线对比介质.
迫切需要有效的废水处理策略,以减轻波罗的海等敏感生态系统的风险.

研究的目的:

分析北欧各地废水废水中的药物和对比剂度.
评估和完善现有的预测模型,用于药品排放到水生生态系统.

主要方法:

在欧洲八个国家的82个废水处理厂 (WWTP) 的废水中分析了35种药物和对比剂.
测量度与总残留方法的预测进行比较,随后使用人类排泄物和WWTP去除率进行模型改进.
在监控的WWTP中对化合物变化的时间分析.

主要成果:

使用总残留方法的初始预测显示与测量数据的相关性很差 (R2 < 0.31).
在纳入人类排泄率后,模型准确性显著提高到R2>0.72,并在WWTP清除率后进一步提高到R2>0.78.
时间分析显示大多数化合物的波动最小,但对比介质的每周变化和 gabapentin 的季节性变化被观察到.

结论:

目前制药排放的预测模型有限,需要改进.
纳入人类分泌/代谢和WWTP去除率对于准确预测水生环境中药物水平至关重要.
改进的模型可以指导更好的废水处理策略,以保护脆弱的生态系统.

关键词:

药物的分泌药物的分泌环境风险评估环境风险评估微污染物的去除微污染物的去除药品销售药品销售药品销售预测的环境度污水处理污水处理污水处理

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