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Updated: Jun 21, 2025

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

Published on: February 20, 2018

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准备好磨你的工具:一个简短的指南,以异构三维G蛋白活性生物传感器

Remi Janicot1, Mikel Garcia-Marcos2

  • 1Department of Biochemistry & Cell Biology, Chobanian & Avedisian School of Medicine (R.J., M.G.-M.) and Department of Biology, College of Arts & Sciences (M.G.-M.), Boston University, Boston, Massachusetts.

Molecular pharmacology
|July 11, 2024
PubMed
概括

光学生物传感器直接测量G蛋白活性,这对于理解G蛋白结合受体 (GPCR) 信号传递至关重要. 本综述评估了各种生物传感器设计,以帮助研究人员选择最佳工具来研究细胞通信和GPCR药理学.

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