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Updated: Jun 21, 2025

Establishment of a Surgically-induced Model in Mice to Investigate the Protective Role of Progranulin in Osteoarthritis
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痛风的发病:从遗传学,表观遗传学和转录遗传学研究中获得的分子见解

Megan P Leask1,2, Tania O Crișan3, Aichang Ji4

  • 1Department of Physiology, University of Otago, Dunedin, Aotearoa, New Zealand.

Nature reviews. Rheumatology
|July 11, 2024
PubMed
概括

痛风的发病包括晶体沉积和免疫反应. 全基因组研究揭示了影响痛风的遗传和表观遗传因素,特别是在调节NLRP3炎症体方面,提供了新的治疗点.

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